Rarely observed features of MacTel:

• A small round yellow spot may be found centered on the fovea, roughly ½-disc diameter size.
• Small retinal hemorrhages in the absence of a neovascular complex. These are transient, usually resolving in a few weeks.
• True lamellar, or full thickness macular holes, may occur. This is a complication of the disease, possibly resulting from the progressive degeneration and atrophy of the retina. Cellular death may destabilize the fovea, leading to a macular hole which may be more difficult to surgically treat than other types of macular holes.
• Neovascular complexes may develop at any time point, and complicate the natural course of the disease. These are most commonly located temporal to the foveola. They seem to originate from the retinal vasculature, not the choroid as is seen in age-related macular degeneration. In MacTel, these neovascular complexes may, however, still gain access to the subretinal space and develop chorio-retinal shunts.